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Purified Rabies Vaccine for human use. Rabies is a preventable viral disease of mammals most often transmitted through the bite of a rabid animal. The vast majority of rabies cases reported each year occur in wild animals like raccoons, skunks, bats, and foxes. Domestic animals account for less than 10% of the reported rabies cases, with cats, cattle, and dogs most often reported rabid. Rabies virus infects the central nervous system, causing encephalopathy and ultimately death. Early symptoms of rabies in humans are nonspecific, consisting of fever, headache, and general malaise. As the disease progresses, neurological symptoms appear and may include insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, agitation, hyper salivation, difficulty swallowing, and hydrophobia (fear of water). Death usually occurs within days of the onset of symptoms. There is no treatment for rabies after symptoms of the disease appear. However, two decades ago scientists developed an extremely effective new rabies vaccine regimen that provides immunity to rabies when administered after an exposure (post-exposure prophylaxis) or for protection before an exposure occurs (pre-exposure prophylaxis). Rabies vaccine for human being is the only effective one for rabies. The persons who were bitten of scratched by dog or cat must get an injection. So, the rabies vaccine has a large market, there are 5 million people need to be injected domestically every year. The hamster kidney cells used in the production of the Yatai vaccine are derived from animals kept in SPF conditions (Specific Pathogen Free). The production process is carried out under strict GMP (Good Manufacturing Practice) conditions. Low Pressure Column Chromatography is used to purify the vaccine. All the purification equipment is imported from the leading company in the field, Pharmacia of Sweden. The purity of the finished product is 99.66%, which leads to a safer and more stable product. The production process produces a finished vaccine of ≥ 2.5 IU / ml. A 100% positive reaction is observed in the serology of the recipient. The product has also been registered by the United Nations Purchasing Office in Copenhagen, Denmark. This office can supply the product to the sub-division of the Secretariat of the UN and the special departments of the UN.
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